Exercise: Obesity Gene’s Effect Reduced By Exercise. With exercise and a physically active lifestyle, the genetic predisposition to obesity caused by the ‘fat mass and obesity associated (FTO) gene can be significantly reduced. The effect of the FTO gene on obesity risk is 27% weaker among physically active adults, compared to those who are physically inactive. These findings challenge the common excuse that “obesity is in my genes.” PLoS Medicine, Oct 2011
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